TY - JOUR AU - Prieto-Garcia, Cristian AU - Hartmann, Oliver AU - Reissland, Michaela AU - Braun, Fabian AU - Fischer, Thomas AU - Walz, Susanne AU - Schülein-Völk, Christina AU - Eilers, Ursula AU - Ade, Carsten P AU - Calzado, Marco A AU - Orian, Amir AU - Maric, Hans M AU - Münch, Christian AU - Rosenfeldt, Mathias AU - Eilers, Martin AU - Diefenbacher, Markus E PY - 2020 DO - 10.15252/emmm.201911101 UR - http://hdl.handle.net/10668/15197 T2 - EMBO molecular medicine AB - The transcription factor ∆Np63 is a master regulator of epithelial cell identity and essential for the survival of squamous cell carcinoma (SCC) of lung, head and neck, oesophagus, cervix and skin. Here, we report that the deubiquitylase USP28... LA - en PB - EMBO Press KW - MYC KW - NOTCH KW - USP28 KW - Squamous cell carcinoma KW - ∆Np63 KW - Animals KW - Carcinoma, squamous cell KW - Epithelial cells KW - Humans KW - Mice KW - Protein stability KW - Trans-activators KW - Transcription factors KW - Tumor suppressor proteins KW - Ubiquitin thiolesterase TI - Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells. TY - research article VL - 12 ER -