RT Journal Article T1 Consumption of fried foods and risk of coronary heart disease: Spanish cohort of the European Prospective Investigation into Cancer and Nutrition study. A1 Guallar-Castillón, Pilar A1 Rodríguez-Artalejo, Fernando A1 Lopez-Garcia, Esther A1 León-Muñoz, Luz M A1 Amiano, Pilar A1 Ardanaz, Eva A1 Arriola, Larraitz A1 Barricarte, Aurelio A1 Buckland, Genevieve A1 Chirlaque, María-Dolores A1 Dorronsoro, Miren A1 Huerta, José-María A1 Larrañaga, Nerea A1 Marin, Pilar A1 Martínez, Carmen A1 Molina, Esther A1 Navarro, Carmen A1 Quirós, J Ramón A1 Rodríguez, Laudina A1 Sanchez-Perez, Maria-Jose A1 González, Carlos A A1 Moreno-Iribas, Conchi K1 Adulto K1 Anciano K1 Angina Pectoris K1 Causas de Muerte K1 Culinaria K1 Enfermedad Coronaria K1 Dieta Mediterránea K1 Femenino K1 Estudios de Seguimiento K1 Humanos K1 Masculino K1 Mediana Edad K1 Infarto del Miocardio K1 Aceites Vegetales K1 Estudios Prospectivos K1 Cuestionarios K1 Factores de Riesgo K1 España AB OBJECTIVETo assess the association between consumption of fried foods and risk of coronary heart disease.DESIGNProspective cohort study.SETTINGSpanish cohort of the European Prospective Investigation into Cancer and Nutrition.PARTICIPANTS40 757 adults aged 29-69 and free of coronary heart disease at baseline (1992-6), followed up until 2004.MAIN OUTCOME MEASURESCoronary heart disease events and vital status identified by record linkage with hospital discharge registers, population based registers of myocardial infarction, and mortality registers.RESULTSDuring a median follow-up of 11 years, 606 coronary heart disease events and 1135 deaths from all causes occurred. Compared with being in the first (lowest) quarter of fried food consumption, the multivariate hazard ratio of coronary heart disease in the second quarter was 1.15 (95% confidence interval 0.91 to 1.45), in the third quarter was 1.07 (0.83 to 1.38), and in the fourth quarter was 1.08 (0.82 to 1.43; P for trend 0.74). The results did not vary between those who used olive oil for frying and those who used sunflower oil. Likewise, no association was observed between fried food consumption and all cause mortality: multivariate hazard ratio for the highest versus the lowest quarter of fried food consumption was 0.93 (95% confidence interval 0.77 to 1.14; P for trend 0.98).CONCLUSIONIn Spain, a Mediterranean country where olive or sunflower oil is used for frying, the consumption of fried foods was not associated with coronary heart disease or with all cause mortality. PB BMJ Publishing Group SN 0959-8138 YR 2012 FD 2012-01-24 LK http://hdl.handle.net/10668/767 UL http://hdl.handle.net/10668/767 LA en NO Guallar-Castillón P, Rodríguez-Artalejo F, Lopez-Garcia E, León-Muñoz LM, Amiano P, Ardanaz E, et al. Consumption of fried foods and risk of coronary heart disease: Spanish cohort of the European Prospective Investigation into Cancer and Nutrition study. BMJ 2012; 344:e363 DS RISalud RD Apr 11, 2025