RT Journal Article
T1 Fruit and vegetable intake and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).
A1 Perez-Cornago, Aurora
A1 Travis, Ruth C
A1 Appleby, Paul N
A1 Tsilidis, Konstantinos K
A1 Tjønneland, Anne
A1 Olsen, Anja
A1 Overvad, Kim
A1 Katzke, Verena
A1 Kühn, Tilman
A1 Trichopoulou, Antonia
A1 Peppa, Eleni
A1 Kritikou, Maria
A1 Sieri, Sabina
A1 Palli, Domenico
A1 Sacerdote, Carlotta
A1 Tumino, Rosario
A1 Bueno-de-Mesquita, H B As
A1 Agudo, Antonio
A1 Larrañaga, Nerea
A1 Molina-Portillo, Elena
A1 Ardanaz, Eva
A1 Chirlaque, Maria-Dolores
A1 Lasheras, Cristina
A1 Stattin, Pär
A1 Wennberg, Maria
A1 Drake, Isabel
A1 Malm, Johan
A1 Schmidt, Julie A
A1 Khaw, Kay-Tee
A1 Gunter, Marc
A1 Freisling, Heinz
A1 Huybrechts, Inge
A1 Aune, Dagfinn
A1 Cross, Amanda J
A1 Riboli, Elio
A1 Key, Timothy J
K1 fruit
K1 prospective
K1 prostate cancer
K1 tumor subtypes
K1 vegetable
AB Several dietary factors have been studied in relation to prostate cancer; however, most studies have not reported on subtypes of fruit and vegetables or tumor characteristics, and results obtained so far are inconclusive. This study aimed to examine the prospective association of total and subtypes of fruit and vegetable intake with the incidence of prostate cancer overall, by grade and stage of disease, and prostate cancer death. Lifestyle information for 142,239 men participating in the European Prospective Investigation into Cancer and Nutrition from 8 European countries was collected at baseline. Multivariable Cox regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). After an average follow-up time of 13.9 years, 7,036 prostate cancer cases were identified. Compared with the lowest fifth, those in the highest fifth of total fruit intake had a significantly reduced prostate cancer risk (HR = 0.91; 95% CI = 0.83-0.99; p-trend = 0.01). No associations between fruit subtypes and prostate cancer risk were observed, except for citrus fruits, where a significant trend was found (HR = 0.94; 95% CI = 0.86-1.02; p-trend = 0.01). No associations between total and subtypes of vegetables and prostate cancer risk were observed. We found no evidence of heterogeneity in these associations by tumor grade and stage, with the exception of significant heterogeneity by tumor grade (pheterogeneity
YR 2017
FD 2017-05-15
LK http://hdl.handle.net/10668/11107
UL http://hdl.handle.net/10668/11107
LA en
DS RISalud
RD Apr 7, 2025