RT Journal Article
T1 One-year changes in fruit and vegetable variety intake and cardiometabolic risk factors changes in a middle-aged Mediterranean population at high cardiovascular risk.
A1 Lopez-Gonzalez, Leyre
A1 Becerra-Tomas, Nerea
A1 Babio, Nancy
A1 Martinez-Gonzalez, Miguel Angel
A1 Nishi, Stephanie K
A1 Corella, Dolores
A1 Goday, Albert
A1 Romaguera, Dora
A1 Vioque, Jesus
A1 Alonso-Gomez, Angel M
A1 Wärnberg, Julia
A1 Martinez, J Alfredo
A1 Serra-Majem, Luis
A1 Estruch, Ramon
A1 Bernal-Lopez, M Rosa
A1 Lapetra, Jose
A1 Pinto, Xavier
A1 Tur, Josep A
A1 Lopez-Miranda, Jose
A1 Bueno-Cavanillas, Aurora
A1 Delgado-Rodriguez, Miguel
A1 Matia-Martin, Pilar
A1 Daimiel, Lidia
A1 Martin-Sanchez, Vicente
A1 Vidal, Josep
A1 Vazquez, Clotilde
A1 Ros, Emilio
A1 Vazquez-Ruiz, Zenaida
A1 Martin-Lujan, Francisco M
A1 Sorli, Jose V
A1 Castañer, Olga
A1 Zulet, M Angeles
A1 Tojal-Sierra, Lucas
A1 Carabaño-Moral, Rosa
A1 Roman-Macia, Josefa
A1 Rayo, Elena
A1 Garcia-Rios, Antonio
A1 Casas, Rosa
A1 Gomez-Perez, Ana M
A1 Santos-Lozano, Jose M
A1 Buil-Cosiales, Pilar
A1 Asensio, Eva M
A1 Lassale, Camille
A1 Abete, Itziar
A1 Salaverria-Lete, Itziar
A1 Sayon-Orea, Carmen
A1 Schröder, Helmut
A1 Salas-Salvado, Jordi
K1 Aged
K1 Body weight
K1 Cardiometabolic risk factors
K1 Cardiovascular diseases
AB Previous studies have shown beneficial associations between fruit and vegetable (FV) consumption and cardiometabolic risk factors. However, variety in FV, which may play an important role on cardiovascular health due to the different nutrient and phytochemical content among the different groups and subgroups of FV has been poorly investigated. We longitudinally investigated associations between 1-year changes in variety and quantity of FV and concurrent changes in cardiometabolic risk factors in elderly subjects with overweight/obesity and metabolic syndrome. a one-year data longitudinal analysis of 6647 PREDIMED-plus study participants (48% women) was conducted. Data were collected at baseline, six months and 1-year of follow-up. Variety and quantity of FV were estimated using a food frequency questionnaire and continuous scores for variety were created based on items/month of FV. Linear mixed-models adjusted for potential confounders were performed to estimate associations (β-coefficients and 95% confidence interval) between 1-year changes in FV variety and/or quantity and concurrent changes in cardiometabolic risk factors. Two points increment in the FV variety score over one year was associated with a concurrent decrease in glucose (-0.33 mg/dL (0.58, -0.07)), body weight (-0.07 kg (-0.13, -0.02)) and waist circumference (WC) (-0.08 cm (-0.16, -10.01)). An increment of 100 g/d of FV over one year was associated with a concurrent decrease in triglycerides (-0.50 mg/dL (-0.93, -0.08)), glucose (-0.21 mg/dL (-0.32, -0.11)), body weight (-0.11 kg (-0.15, -0.07)) and WC (-0.10 cm (-0.14, -0.06)) over 1-year. Changes in FV consumption which led to higher quantity and variety over one year were associated with downward changes in glucose (-1.26 mg/dL (-2.09, -0.43)), body weight (-0.40 kg (-0.58, -0.23)) and WC (-0.50 cm (-0.73, -0.28)). Greater variety, in combination with higher quantity of FV was significantly associated with a decrease in several cardiometabolic risk factors among elderly subjects at high cardiovascular risk.
PB Nature Publishing Group
YR 2022
FD 2022-03-14
LK http://hdl.handle.net/10668/19532
UL http://hdl.handle.net/10668/19532
LA en
NO López-González L, Becerra-Tomás N, Babio N, Martínez-González MÁ, Nishi SK, Corella D, et al. One-year changes in fruit and vegetable variety intake and cardiometabolic risk factors changes in a middle-aged Mediterranean population at high cardiovascular risk. Eur J Clin Nutr. 2022 Oct;76(10):1393-1402
NO CIBEROBN, CIBERESP and CIBERDEM are initiatives of the Carlos III Health Institute, Spain. The PREDIMED-Plus trial was supported by the Spanish government’s official funding agency for biomedical research, ISCIII, through the Fondo de Investigación para la Salud (FIS) and co-funded by European Union ERDF/ESF, “A way to make Europe”/ “Investing in your future” (five coordinated FIS projects led by JS-S and JVid, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123,PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215,PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560 and PI19/01332), the Special Action Project entitled: Implementación y evaluación de una intervención intensiva sobre la actividad física Cohorte PREDIMED-Plus grant to JS-S,the European Research Council (Advanced Research Grant 2013–2018, 340918) to MÁM-G, the Recercaixa Grant to JS-S (2013ACUP00194), grants from the Consejería de Salud de la Junta de Andalucía (PI0458/2013, PS0358/2016 and PI0137/2018), a grant from the Generalitat Valenciana (PROMETEO/2017/017), a SEMERGEN grant, and funds from the European Regional Development Fund (CB06/03). Study resulting from the SLT006/17/00246 grant was funded by the Department of Health of theGeneralitat de Catalunya by the call “Acció instrumental de programes de recerca orientats en l’àmbit de la recerca i la innovació en salut.” We thank CERCA Programme/Generalitat de Catalunya for institutional support. This work is partially supported by ICREA under the ICREA Academia program. LL-G receives a predoctoral grant from the University of Rovira i Virgili (2019PMF-PIPF-16). SKN is supported by a postdoctoral fellowship from the Canadian Institutes of Health Research (CIHR) and isa volunteer member of the non-for profit group Plant Based Canada.
DS RISalud
RD Apr 19, 2025