RT Journal Article T1 Chronic kidney disease in Spain: Prevalence and impact of accumulation of cardiovascular risk factors. T2 Prevalencia de enfermedad renal crónica en España: impacto de la acumulación de factores de riesgo cardiovascular. A1 Gorostidi, Manuel A1 Sánchez-Martínez, Mercedes A1 Ruilope, Luis M A1 Graciani, Auxiliadora A1 de la Cruz, Juan J A1 Santamaría, Rafael A1 Del Pino, María D A1 Guallar-Castillón, Pilar A1 de Álvaro, Fernando A1 Rodríguez-Artalejo, Fernando A1 Banegas, José R K1 Cardiovascular disease K1 Chronic kidney disease K1 Enfermedad cardiovascular K1 Enfermedad renal crónica K1 Epidemiology K1 Epidemiología K1 Prevalence K1 Prevalencia K1 Public health K1 Salud pública AB Chronic kidney disease (CKD) is a public health problem worldwide. We aimed to estimate the CKD prevalence in Spain and to examine the impact of the accumulation of cardiovascular risk factors (CVRF). We performed a nationwide, population-based survey evaluating 11,505 individuals representative of the Spanish adult population. Information was collected through standardised questionnaires, physical examination, and analysis of blood and urine samples in a central laboratory. CKD was graded according to current KDIGO definitions. The relationship between CKD and 10CVRF was assessed (age, hypertension, general obesity, abdominal obesity, smoking, high LDL-cholesterol, low HDL-cholesterol, hypertriglyceridaemia, diabetes and sedentary lifestyle). Prevalence of CKD was 15.1% (95%CI: 14.3-16.0%). CKD was more common in men (23.1% vs 7.3% in women), increased with age (4.8% in 18-44 age group, 17.4% in 45-64 age group, and 37.3% in ≥65), and was more common in those with than those without cardiovascular disease (39.8% vs 14.6%); all P CKD affects one in seven adults in Spain. The prevalence is higher than previously reported and similar to that in the United States. CKD was particularly prevalent in men, older people and people with cardiovascular disease. Prevalence of CKD increased considerably with the accumulation of CVRF, suggesting that CKD could be considered as a cardiovascular condition. YR 2018 FD 2018-06-18 LK http://hdl.handle.net/10668/12607 UL http://hdl.handle.net/10668/12607 LA en LA es DS RISalud RD Apr 7, 2025