RT Journal Article
T1 Risk factors for non-diabetic renal disease in diabetic patients.
A1 Bermejo, Sheila
A1 González, Ester
A1 López-Revuelta, Katia
A1 Ibernon, Meritxell
A1 López, Diana
A1 Martín-Gómez, Adoración
A1 Garcia-Osuna, Rosa
A1 Linares, Tania
A1 Díaz, Montserrat
A1 Martín, Nàdia
A1 Barros, Xoana
A1 Marco, Helena
A1 Navarro, Maruja Isabel
A1 Esparza, Noemí
A1 Elias, Sandra
A1 Coloma, Ana
A1 Robles, Nicolás Roberto
A1 Agraz, Irene
A1 Poch, Esteban
A1 Rodas, Lida
A1 Lozano, Víctor
A1 Fernández, Beatriz
A1 Hernández, Eduardo
A1 Martínez, Maria Isabel
A1 Stanescu, Ramona Ionela
A1 Moirón, José Pelayo
A1 García, Núria
A1 Goicoechea, Marian
A1 Calero, Francesca
A1 Bonet, Josep
A1 Galceran, Josep M
A1 Liaño, Fernando
A1 Pascual, Julio
A1 Praga, Manuel
A1 Fulladosa, Xavier
A1 Soler, María José
K1 chronic kidney disease
K1 diabetes mellitus
K1 diabetic nephropathy
K1 non-diabetic renal disease
K1 renal biopsy
AB Diabetic patients with kidney disease have a high prevalence of non-diabetic renal disease (NDRD). Renal and patient survival regarding the diagnosis of diabetic nephropathy (DN) or NDRD have not been widely studied. The aim of our study is to evaluate the prevalence of NDRD in patients with diabetes and to determine the capacity of clinical and analytical data in the prediction of NDRD. In addition, we will study renal and patient prognosis according to the renal biopsy findings in patients with diabetes. Retrospective multicentre observational study of renal biopsies performed in patients with diabetes from 2002 to 2014. In total, 832 patients were included: 621 men (74.6%), mean age of 61.7 ± 12.8 years, creatinine was 2.8 ± 2.2 mg/dL and proteinuria 2.7 (interquartile range: 1.2-5.4) g/24 h. About 39.5% (n = 329) of patients had DN, 49.6% (n = 413) NDRD and 10.8% (n = 90) mixed forms. The most frequent NDRD was nephroangiosclerosis (NAS) (n = 87, 9.3%). In the multivariate logistic regression analysis, older age [odds ratio (OR) = 1.03, 95% CI: 1.02-1.05, P  The most frequent cause of NDRD is NAS. Elderly patients with microhaematuria and the absence of DR are the ones at risk for NDRD. Patients with DN presented worse renal prognosis and higher mortality than those with NDRD. These results suggest that in some patients with diabetes, kidney biopsy may be useful for an accurate renal diagnosis and subsequently treatment and prognosis.
SN 2048-8505
YR 2020
FD 2020-01-03
LK http://hdl.handle.net/10668/15978
UL http://hdl.handle.net/10668/15978
LA en
DS RISalud
RD Apr 9, 2025