TY - JOUR AU - Schumann, Gerald G. AU - Fuchs, Nina V. AU - Tristán-Ramos, Pablo AU - Sebe, Attila AU - Ivics, Zoltán AU - Heras, Sara R. PY - 2019 DO - 10.1186/s13100-019-0151-x UR - http://hdl.handle.net/10668/3151 T2 - Mobile DNA AB - Human stem cells harbor significant potential for basic and clinical translational research as well as regenerative medicine. Currently ~ 3000 adult and ~ 30 pluripotent stem cell-based, interventional clinical trials are ongoing worldwide, and... LA - en PB - BioMed Central Ltd. KW - Adult stem cells KW - Genomic destabilization KW - LINE-1 KW - Methylation KW - Pluripotent stem cells KW - Regenerative medicine KW - Restriction KW - Transposable elements KW - Células madre adultas KW - Genomic instability KW - Inestabilidad genómica KW - Metilación KW - Células madre pluripotentes KW - Medicina regenerativa KW - Elementos transponibles de ADN KW - DNA transposable elements KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Adult Stem Cells KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Methylation KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Pluripotent Stem Cells KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Interspersed Repetitive Sequences::DNA Transposable Elements KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genomic Instability TI - The impact of transposable element activity on therapeutically relevant human stem cells TY - research article ER -