TY - JOUR AU - Van Cutsem, Eric AU - Mayer, Robert J AU - Laurent, Stéphanie AU - Winkler, Robert AU - Grávalos, Cristina AU - Benavides, Manuel AU - Longo-Munoz, Federico AU - Portales, Fabienne AU - Ciardiello, Fortunato AU - Siena, Salvatore AU - Yamaguchi, Kensei AU - Muro, Kei AU - Denda, Tadamichi AU - Tsuji, Yasushi AU - Makris, Lukas AU - Loehrer, Patrick AU - Lenz, Heinz-Josef AU - Ohtsu, Atsushi AU - RECOURSE Study Group PY - 2017 DO - 10.1016/j.ejca.2017.10.009 UR - http://hdl.handle.net/10668/11947 T2 - European journal of cancer (Oxford, England : 1990) AB - In the phase III RECOURSE trial, trifluridine/tipiracil (TAS-102) extended overall survival (OS) and progression-free survival (PFS) with an acceptable toxicity profile in patients with metastatic colorectal cancer refractory or intolerant to standard... LA - en KW - Fluoropyrimidine KW - Metastatic colorectal cancer KW - Randomised controlled trial KW - TAS-102 KW - Tipiracil KW - Trifluridine KW - Adult KW - Aged KW - Antineoplastic Combined Chemotherapy Protocols KW - Colorectal Neoplasms KW - Disease-Free Survival KW - Double-Blind Method KW - Drug Combinations KW - Female KW - Humans KW - Kaplan-Meier Estimate KW - Male KW - Middle Aged KW - Proportional Hazards Models KW - Pyrrolidines KW - Thymine KW - Treatment Outcome KW - Trifluridine KW - Uracil TI - The subgroups of the phase III RECOURSE trial of trifluridine/tipiracil (TAS-102) versus placebo with best supportive care in patients with metastatic colorectal cancer. TY - research article VL - 90 ER -