TY  - JOUR
AU  - Prieto-Garcia, Cristian
AU  - Hartmann, Oliver
AU  - Reissland, Michaela
AU  - Braun, Fabian
AU  - Bozkurt, Süleyman
AU  - Pahor, Nikolett
AU  - Fuss, Carmina
AU  - Schirbel, Andreas
AU  - Schülein-Völk, Christina
AU  - Buchberger, Alexander
AU  - Calzado Canale, Marco A
AU  - Rosenfeldt, Mathias
AU  - Dikic, Ivan
AU  - Münch, Christian
AU  - Diefenbacher, Markus E
PY  - 2022
DO  - 10.1002/1878-0261.13217
UR  - http://hdl.handle.net/10668/19619
T2  - Molecular oncology
AB  - Oncogenic transformation of lung epithelial cells is a multistep process, frequently starting with the inactivation of tumour suppressors and subsequent development of activating mutations in proto-oncogenes, such as members of the PI3K or MAPK...
LA  - en
PB  - John Wiley & Sons
KW  - USP28
KW  - Buparlisib
KW  - c-MYC
KW  - Gefitinib
KW  - Lung cancer
KW  - Vemurafenib
KW  - Carcinogenesis
KW  - Cell line, tumor
KW  - Cell transformation, neoplastic
KW  - ErbB receptors
KW  - Humans
KW  - Phosphatidylinositol 3-kinases
KW  - Proto-oncogene proteins B-raf
KW  - Transcription factors
KW  - Ubiquitin thiolesterase
TI  - USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K.
TY  - research article
VL  - 16
ER  -