TY - JOUR AU - Czub, Barbara AU - Shah, Amna Z AU - Alfano, Giovanna AU - Kruczek, Przemysław M AU - Chakarova, Christina F AU - Bhattacharya, Shomi S PY - 2016 DO - 10.1371/journal.pone.0148678 UR - http://hdl.handle.net/10668/9831 T2 - PloS one AB - The significance of the ubiquitin-proteasome system (UPS) for protein degradation has been highlighted in the context of neurodegenerative diseases, including retinal dystrophies. TOPORS, a dual E3 ubiquitin and SUMO1 ligase, forms a component of the... LA - en KW - ATPases Associated with Diverse Cellular Activities KW - Adenosine Triphosphatases KW - Animals KW - Cell Line KW - DNA, Complementary KW - Humans KW - Mice KW - Mutation KW - Neoplasm Proteins KW - Nuclear Proteins KW - Proteasome Endopeptidase Complex KW - Protein Interaction Maps KW - Retina KW - Ubiquitin KW - Ubiquitin-Protein Ligases TI - TOPORS, a Dual E3 Ubiquitin and Sumo1 Ligase, Interacts with 26 S Protease Regulatory Subunit 4, Encoded by the PSMC1 Gene. TY - research article VL - 11 ER -