RT Journal Article T1 COVID-19 pandemic, mechanical reperfusion and 30-day mortality in ST elevation myocardial infarction. A1 De Luca, Giuseppe A1 Algowhary, Magdy A1 Uguz, Berat A1 Oliveira, Dinaldo C A1 Ganyukov, Vladimir A1 Zimbakov, Zan A1 Cercek, Miha A1 Jensen, Lisette Okkels A1 Loh, Poay Huan A1 Calmac, Lucian A1 Roura-Ferrer, Gerard A1 Quadros, Alexandre A1 Milewski, Marek A1 Scotto di Uccio, Fortunato A1 von Birgelen, Clemens A1 Versaci, Francesco A1 Ten Berg, Jurriën A1 Casella, Gianni A1 Wong, Aaron Sung Lung A1 Kala, Petr A1 Diez Gil, Jose Luis A1 Carrillo, Xavier A1 Dirksen, Maurits Theodoor A1 Becerra-Muñoz, Víctor Manuel A1 Kang-Yin Lee, Michael A1 Juzar, Dafsah A A1 de Moura Joaquim, Rodrigo A1 Paladino, Roberto A1 Milicic, Davor A1 Davlouros, Periklis A1 Bakraceski, Nikola A1 Zilio, Filippo A1 Donazzan, Luca A1 Kraaijeveld, Adriaan O A1 Galasso, Gennaro A1 Lux, Arpad A1 Marinucci, Lucia A1 Guiducci, Vincenzo A1 Menichelli, Maurizio A1 Scoccia, Alessandra A1 Yamac, Aylin A1 Ugur Mert, Kadir A1 Flores Rios, Xacobe A1 Kovarnik, Tomas A1 Kidawa, Michal A1 Moreu, Jose A1 Flavien, Vincent A1 Fabris, Enrico A1 Lozano Martìnez-Luengas, Iñigo A1 Boccalatte, Marco A1 Bosa Ojeda, Francisco A1 Arellano-Serrano, Carlos A1 Caiazzo, Gianluca A1 Cirrincione, Giuseppe A1 Kao, Hsien-Li A1 Sanchis Fores, Juan A1 Vignali, Luigi A1 Pereira, Helder A1 Manzo-Silberman, Stéphane A1 Ordonez, Santiago A1 Özkan, Alev Arat A1 Scheller, Bruno A1 Lehtola, Heidi A1 Teles, Rui A1 Mantis, Christos A1 Ylitalo, Antti A1 Brum Silveira, Joao Antonio A1 Zoni, Rodrigo A1 Bessonov, Ivan A1 Savonitto, Stefano A1 Kochiadakis, George A1 Alexopoulos, Dimitrios A1 Uribe, Carlos A1 Kanakakis, John A1 Faurie, Benjamin A1 Gabrielli, Gabriele A1 Gutiérrez, Alejandro A1 Bachini, Juan Pablo A1 Rocha, Alex A1 Tam, Franckie Cc A1 Rodriguez, Alfredo A1 Lukito, Antonia A1 Saint-Joy, Veauthyelau A1 Pessah, Gustavo A1 Tuccillo, Bernardino A1 Cortese, Giuliana A1 Parodi, Guido A1 Bouraghda, Mohamed Abed A1 Kedhi, Elvin A1 Lamelas, Pablo A1 Suryapranata, Harry A1 Nardin, Matteo A1 Verdoia, Monica A1 ISACS-STEMI COVID-19, A1 Collaborators, K1 COVID-19 K1 myocardial infarction K1 percutaneous coronary intervention AB The initial data of the International Study on Acute Coronary Syndromes - ST Elevation Myocardial Infarction COVID-19 showed in Europe a remarkable reduction in primary percutaneous coronary intervention procedures and higher in-hospital mortality during the initial phase of the pandemic as compared with the prepandemic period. The aim of the current study was to provide the final results of the registry, subsequently extended outside Europe with a larger inclusion period (up to June 2020) and longer follow-up (up to 30 days). This is a retrospective multicentre registry in 109 high-volume primary percutaneous coronary intervention (PPCI) centres from Europe, Latin America, South-East Asia and North Africa, enrolling 16 674 patients with ST segment elevation myocardial infarction (STEMI) undergoing PPPCI in March/June 2019 and 2020. The main study outcomes were the incidence of PPCI, delayed treatment (ischaemia time >12 hours and door-to-balloon >30 min), in-hospital and 30-day mortality. In 2020, during the pandemic, there was a significant reduction in PPCI as compared with 2019 (incidence rate ratio 0.843, 95% CI 0.825 to 0.861, p75 years) (p=0.015), and was not related to the peak of cases or deaths due to COVID-19. The heterogeneity among centres was high (p Percutaneous revascularisation for STEMI was significantly affected by the COVID-19 pandemic, with a 16% reduction in PPCI procedures, especially among older patients (about 20%), and longer delays to treatment, which may have contributed to the increased in-hospital and 30-day mortality during the pandemic. NCT04412655. YR 2021 FD 2021-10-28 LK http://hdl.handle.net/10668/20156 UL http://hdl.handle.net/10668/20156 LA en DS RISalud RD Apr 20, 2025