TY  - JOUR
AU  - Pulido, María
AU  - Chamorro, Virginia
AU  - Romero, Irene
AU  - Algarra, Ignacio
AU  - S-Montalvo, Alba
AU  - Collado, Antonia
AU  - Garrido, Federico
AU  - Garcia-Lora, Angel M.
PY  - 2020
DO  - 10.3390/cancers12061563
UR  - http://hdl.handle.net/10668/4127
T2  - Cancers
AB  - The capacity of cytotoxic-T lymphocytes to recognize and destroy tumor cells depends on the surface expression by tumor cells of MHC class I molecules loaded with tumor antigen peptides. Loss of MHC-I expression is the most frequent mechanism by which...
LA  - en
PB  - MDPI
KW  - MHC-I restoration
KW  - Fhit
KW  - Antitumor immunity
KW  - Immune profile
KW  - Cytotoxic t lymphocytes
KW  - Immunotherapy
KW  - Vaccine
KW  - Tumor cells
KW  - Mice
KW  - Linfocitos t citotóxicos
KW  - Vacuna
KW  - Ratones
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Histocompatibility Antigens::Histocompatibility Antigens Class I
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Neoplasm
KW  - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Cytokine-Induced Killer Cells::T-Lymphocytes, Cytotoxic
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Gene Transfer Techniques::Transfection
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Immunomodulation::Immunotherapy
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides
KW  - Medical Subject Headings::Chemicals and Drugs::Complex Mixtures::Biological Products::Vaccines
TI  - Restoration of MHC-I on Tumor Cells by Fhit Transfection Promotes Immune Rejection and Acts as an Individualized Immunotherapeutic Vaccine
TY  - research article
ER  -