%0 Journal Article %A O'Valle, Francisco %A de Buitrago, Juan G %A Hernández-Cortés, Pedro %A Padial-Molina, Miguel %A Crespo-Lora, Vicente %A Cobo, Marien %A Aguilar, David %A Galindo-Moreno, Pablo %T Increased Expression of Musashi-1 Evidences Mesenchymal Repair in Maxillary Sinus Floor Elevation. %D 2018 %U http://hdl.handle.net/10668/12845 %X This study aimed to analyze the expression of Musashi-1 (MSI1) in maxillary native bone and grafted bone after maxillary sinus floor elevation. To do so, fifty-seven bone biopsies from 45 participants were studied. Eighteen samples were collected from native bone while 39 were obtained 6 months after maxillary sinus grafting procedures. Musashi-1 was analyzed by immunohistochemistry and RT-PCR. MSI1 was detected in osteoblasts and osteocytes in 97.4% (38/39) of grafted areas. In native bone, MSI1 was detected in only 66.6% (12/18) of the biopsies, mainly in osteocytes. Detection of MSI1 was significantly higher in osteoprogenitor mesenchymal cells of grafted biopsies (p  %~