RT Journal Article T1 Important Unresolved Questions in the Management of Hepatic Encephalopathy: An ISHEN Consensus. A1 Bajaj, Jasmohan S A1 Lauridsen, Mette A1 Tapper, Elliot B A1 Duarte-Rojo, Andres A1 Rahimi, Robert S A1 Tandon, Puneeta A1 Shawcross, Debbie L A1 Thabut, Dominique A1 Dhiman, Radha K A1 Romero-Gomez, Manuel A1 Sharma, Barjesh C A1 Montagnese, Sara AB Management of hepatic encephalopathy (HE) remains challenging from a medical and psychosocial perspective. Members of the International Society for Hepatic Encephalopathy and Nitrogen Metabolism recognized 5 key unresolved questions in HE management focused on (i) driving, (ii) ammonia levels in clinical practice, (iii) testing strategies for covert or minimal HE, (iv) therapeutic options, and (v) nutrition and patient-reported outcomes. The consensus document addresses these topical issues with a succinct review of the literature and statements that critically evaluate the current science and practice, laying the groundwork for future investigations. YR 2020 FD 2020 LK http://hdl.handle.net/10668/15868 UL http://hdl.handle.net/10668/15868 LA en DS RISalud RD Apr 17, 2025