TY - JOUR AU - Huertas-Castaño, Carlos AU - Gómez-Muñoz, María A. AU - Pardal, Ricardo AU - Vega, Francisco M. PY - 2019 DO - 10.3390/ijms21010039 UR - http://hdl.handle.net/10668/3768 T2 - International Journal of Molecular Sciences AB - Neuroblastoma is the most frequent extracranial solid tumour in children, causing 10% of all paediatric oncology deaths. It arises in the embryonic neural crest due to an uncontrolled behaviour of sympathetic nervous system progenitors, giving rise to... LA - en PB - MDPI KW - Neuroblastoma KW - Hypoxia KW - Neural crest cells KW - Cancer stem cells KW - Paediatric oncology KW - Hipoxia KW - Cresta neural KW - Células madre neoplásicas KW - Oncología médica KW - Pediatría KW - Hipoxia tumoral KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation KW - Medical Subject Headings::Persons::Persons::Age Groups::Child KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Progression KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Neoplasm Metastasis KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Glandular and Epithelial::Neoplasms, Neuroepithelial::Neuroectodermal Tumors, Primitive::Neuroectodermal Tumors, Primitive, Peripheral::Neuroblastoma KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence::Regulatory Sequences, Nucleic Acid::Gene Regulatory Networks KW - Medical Subject Headings::Disciplines and Occupations::Health Occupations::Medicine::Internal Medicine::Medical Oncology KW - Medical Subject Headings::Disciplines and Occupations::Health Occupations::Medicine::Pediatrics KW - Medical Subject Headings::Anatomy::Embryonic Structures::Neural Crest KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Respiration::Cell Hypoxia KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical TI - Hypoxia in the Initiation and Progression of Neuroblastoma Tumours TY - review article ER -