RT Journal Article T1 Coffee Drinking and Mortality in 10 European Countries: A Multinational Cohort Study. A1 Gunter, Marc J A1 Murphy, Neil A1 Cross, Amanda J A1 Dossus, Laure A1 Dartois, Laureen A1 Fagherazzi, Guy A1 Kaaks, Rudolf A1 Kühn, Tilman A1 Boeing, Heiner A1 Aleksandrova, Krasimira A1 Tjønneland, Anne A1 Olsen, Anja A1 Overvad, Kim A1 Larsen, Sofus Christian A1 Redondo Cornejo, Maria Luisa A1 Agudo, Antonio A1 Sanchez-Perez, Maria-Jose A1 Altzibar, Jone M A1 Navarro, Carmen A1 Ardanaz, Eva A1 Khaw, Kay-Tee A1 Butterworth, Adam A1 Bradbury, Kathryn E A1 Trichopoulou, Antonia A1 Lagiou, Pagona A1 Trichopoulos, Dimitrios A1 Palli, Domenico A1 Grioni, Sara A1 Vineis, Paolo A1 Panico, Salvatore A1 Tumino, Rosario A1 Bueno-de-Mesquita, Bas A1 Siersema, Peter A1 Leenders, Max A1 Beulens, Joline W J A1 Uiterwaal, Cuno U A1 Wallström, Peter A1 Nilsson, Lena Maria A1 Landberg, Rikard A1 Weiderpass, Elisabete A1 Skeie, Guri A1 Braaten, Tonje A1 Brennan, Paul A1 Licaj, Idlir A1 Muller, David C A1 Sinha, Rashmi A1 Wareham, Nick A1 Riboli, Elio AB The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. To examine whether coffee consumption is associated with all-cause and cause-specific mortality. Prospective cohort study. 10 European countries. 521 330 persons enrolled in EPIC (European Prospective Investigation into Cancer and Nutrition). Hazard ratios (HRs) and 95% CIs estimated using multivariable Cox proportional hazards models. The association of coffee consumption with serum biomarkers of liver function, inflammation, and metabolic health was evaluated in the EPIC Biomarkers subcohort (n = 14 800). During a mean follow-up of 16.4 years, 41 693 deaths occurred. Compared with nonconsumers, participants in the highest quartile of coffee consumption had statistically significantly lower all-cause mortality (men: HR, 0.88 [95% CI, 0.82 to 0.95]; P for trend  Reverse causality may have biased the findings; however, results did not differ after exclusion of participants who died within 8 years of baseline. Coffee-drinking habits were assessed only once. Coffee drinking was associated with reduced risk for death from various causes. This relationship did not vary by country. European Commission Directorate-General for Health and Consumers and International Agency for Research on Cancer. YR 2017 FD 2017-07-11 LK http://hdl.handle.net/10668/11389 UL http://hdl.handle.net/10668/11389 LA en DS RISalud RD Apr 11, 2025