TY  - JOUR
AU  - Ariza, Adriana
AU  - Collado, Daniel
AU  - Vida, Yolanda
AU  - Montañez, María I
AU  - Pérez-Inestrosa, Ezequiel
AU  - Blanca, Miguel
AU  - Torres, María José
AU  - Cañada, F Javier
AU  - Pérez-Sala, Dolores
PY  - 2014
DO  - 10.1371/journal.pone.0090891
UR  - http://hdl.handle.net/10668/1985
T2  - PloS ONE
AB  - Allergic reactions towards β-lactam antibiotics pose an important clinical problem. The ability of small molecules, such as a β-lactams, to bind covalently to proteins, in a process known as haptenation, is considered necessary for induction of a...
LA  - en
PB  - Public Library of Science
KW  - Animales
KW  - Antibacterianos
KW  - Biotinilación
KW  - Butilaminas
KW  - Haptenos
KW  - Hipersensibilidad
KW  - Amoxicilina
KW  - Inmunoglobulina E
KW  - Macrófagos
KW  - Estructura molecular
KW  - Beta-lactamas
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Binding, Competitive
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Biotinylation
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amines::Butylamines
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Epitopes::Haptens
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Diseases::Immune System Diseases::Hypersensitivity
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Globulins::Serum Globulins::Immunoglobulins::Antibodies::Immunoglobulin Isotypes::Immunoglobulin E
KW  - Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System::Phagocytes::Macrophages
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Microscopy::Microscopy, Confocal
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Molecular Structure
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Albumins::Serum Albumin
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Penicillins::Penicillin G::Ampicillin::Amoxicillin
TI  - Study of protein haptenation by amoxicillin through the use of a biotinylated antibiotic.
TY  - research article
ER  -