TY - JOUR AU - Paz-Ares, Luis G AU - Ramalingam, Suresh S AU - Ciuleanu, Tudor-Eliade AU - Lee, Jong-Seok AU - Urban, Laszlo AU - Caro, Reyes Bernabe AU - Park, Keunchil AU - Sakai, Hiroshi AU - Ohe, Yuichiro AU - Nishio, Makoto AU - Audigier-Valette, Clarisse AU - Burgers, Jacobus A AU - Pluzanski, Adam AU - Sangha, Randeep AU - Gallardo, Carlos AU - Takeda, Masayuki AU - Linardou, Helena AU - Lupinacci, Lorena AU - Lee, Ki Hyeong AU - Caserta, Claudia AU - Provencio, Mariano AU - Carcereny, Enric AU - Otterson, Gregory A AU - Schenker, Michael AU - Zurawski, Bogdan AU - Alexandru, Aurelia AU - Vergnenegre, Alain AU - Raimbourg, Judith AU - Feeney, Kynan AU - Kim, Sang-We AU - Borghaei, Hossein AU - O'Byrne, Kenneth John AU - Hellmann, Matthew D AU - Memaj, Arteid AU - Nathan, Faith Ellen AU - Bushong, Judith AU - Tran, Phuong AU - Brahmer, Julie R AU - Reck, Martin PY - 2021 DO - 10.1016/j.jtho.2021.09.010 UR - http://hdl.handle.net/10668/22342 T2 - Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer AB - In CheckMate 227, nivolumab plus ipilimumab prolonged overall survival (OS) versus chemotherapy in patients with tumor programmed death-ligand 1 (PD-L1) greater than or equal to 1% (primary end point) or less than 1% (prespecified descriptive... LA - en KW - CTLA-4 KW - First-line KW - Immunotherapy KW - Metastatic non–small cell lung cancer KW - PD-1 checkpoint inhibitor KW - Adult KW - Antineoplastic Combined Chemotherapy Protocols KW - Humans KW - Ipilimumab KW - Lung Neoplasms KW - Neoplasm Recurrence, Local KW - Nivolumab TI - First-Line Nivolumab Plus Ipilimumab in Advanced NSCLC: 4-Year Outcomes From the Randomized, Open-Label, Phase 3 CheckMate 227 Part 1 Trial. TY - research article VL - 17 ER -