%0 Journal Article %A López-Díaz, Álvaro %A Murillo-Izquierdo, Manuel %A Moreno-Mellado, Elisa %T Off-label use of ketamine for treatment-resistant depression in clinical practice: European perspective. %D 2019 %U http://hdl.handle.net/10668/13886 %X Ketamine therapy for treatment-resistant depression in European national health systems may only be considered after attempting all evidence-based antidepressant strategies outlined in clinical guidelines. This paper seeks to explain the ethical, regulatory and procedural framework for the off-label use of ketamine for treatment-resistant depression within a public healthcare system.Declaration of interestNone. %K Treatment-resistant depression %K antidepressants %K ketamine %~