TY - JOUR AU - Sarmiento-Maldonado, Mauricio AU - Ramirez-Villanueva, Pablo AU - Cortes-Monroy, Pablo Bertin AU - Jara-Arias, Veronica AU - Soto-Donoso, Katherine AU - Uribe-Gonzalez, Pablo AU - Ocqueteau-Tachini, Mauricio AU - Perez-Simon, Jose Antonio PY - 2017 DO - 10.1186/s40164-017-0092-3 SN - 2162-3619 UR - https://hdl.handle.net/10668/27873 T2 - Experimental hematology & oncology AB - Ruxolitinib is a potent inhibitor of JAK1/2 with proven efficacy in myelofibrosis. In recent years, research in graft versus host disease (GVHD) has revealed the role of activation of JAK pathways in alloreactive lymphocytes. Some reports have shown... LA - en KW - Corticoid refractoriness KW - Extracorporeal photopheresis KW - Graft versus host disease KW - Ruxolitinib KW - Primary Myelofibrosis KW - Photopheresis KW - Graft vs Host Disease KW - Bronchiolitis Obliterans Syndrome KW - Steroids TI - Compassionate use of ruxolitinib in acute and chronic graft versus host disease refractory both to corticosteroids and extracorporeal photopheresis. TY - research article VL - 6 ER -