RT Journal Article
T1 EEG abnormalities and clinical phenotypes in pre-school children with autism spectrum disorder.
A1 Romero-Gonzalez, Marina
A1 Navas-Sanchez, Patricia
A1 Marin-Gamez, Ester
A1 Barbancho-Fernandez, Miguel Angel
A1 Fernandez-Sanchez, Victoria Eugenia
A1 Lara-Muñoz, Jose Pablo
A1 Guzman-Parra, Jose
K1 Autism spectrum disorder
K1 Clinical features
K1 EEG abnormalities
K1 Pre-school children
AB Abnormalities on electroencephalography (EEG) results have been reported in a high percentage of children with Autism Spectrum Disorder (ASD). The purpose of this study was to explore the prevalence of EEG abnormalities in a clinical population of pre-school children with Autism Spectrum Disorder and the differences in terms of the following phenotypic characteristics: adaptive behavior, executive functioning, severity of Autism Spectrum Disorder core symptoms, and comorbidity symptoms. A cross-sectional analysis of 69 children who attended the Autism Spectrum Disorder early diagnosis program with electroencephalography and clinical diagnosis was performed. A battery of questionnaires was also made to parents to evaluate emotions, behavior, and functional skills for daily living. Out of 69 pre-school children with Autism Spectrum Disorder, twenty nine (42%) had abnormalities in electroencephalography results. The group with abnormal epileptiform electroencephalography exhibited more impairment in executive functioning and social-relationship coexisting symptoms. The presence of an abnormal epileptiform electroencephalography in pre-school children with ASD already suggests a worse development in clinical features.
PB Elsevier
YR 2022
FD 2022-03-15
LK http://hdl.handle.net/10668/22545
UL http://hdl.handle.net/10668/22545
LA en
NO Romero-González M, Navas-Sánchez P, Marín-Gámez E, Barbancho-Fernández MA, Fernández-Sánchez VE, Lara-Muñoz JP, et al. EEG abnormalities and clinical phenotypes in pre-school children with autism spectrum disorder. Epilepsy Behav. 2022 Apr;129:108619
DS RISalud
RD Apr 11, 2025