%0 Journal Article
%A Romero-Gonzalez, Marina
%A Navas-Sanchez, Patricia
%A Marin-Gamez, Ester
%A Barbancho-Fernandez, Miguel Angel
%A Fernandez-Sanchez, Victoria Eugenia
%A Lara-Muñoz, Jose Pablo
%A Guzman-Parra, Jose
%T EEG abnormalities and clinical phenotypes in pre-school children with autism spectrum disorder.
%D 2022
%U http://hdl.handle.net/10668/22545
%X Abnormalities on electroencephalography (EEG) results have been reported in a high percentage of children with Autism Spectrum Disorder (ASD). The purpose of this study was to explore the prevalence of EEG abnormalities in a clinical population of pre-school children with Autism Spectrum Disorder and the differences in terms of the following phenotypic characteristics: adaptive behavior, executive functioning, severity of Autism Spectrum Disorder core symptoms, and comorbidity symptoms. A cross-sectional analysis of 69 children who attended the Autism Spectrum Disorder early diagnosis program with electroencephalography and clinical diagnosis was performed. A battery of questionnaires was also made to parents to evaluate emotions, behavior, and functional skills for daily living. Out of 69 pre-school children with Autism Spectrum Disorder, twenty nine (42%) had abnormalities in electroencephalography results. The group with abnormal epileptiform electroencephalography exhibited more impairment in executive functioning and social-relationship coexisting symptoms. The presence of an abnormal epileptiform electroencephalography in pre-school children with ASD already suggests a worse development in clinical features.
%K Autism spectrum disorder
%K Clinical features
%K EEG abnormalities
%K Pre-school children
%~