TY - JOUR AU - Corella, Dolores AU - Coltell, Oscar AU - Sorlí, Jose V AU - Estruch, Ramón AU - Quiles, Laura AU - Martínez-González, Miguel Ángel AU - Salas-Salvadó, Jordi AU - Castañer, Olga AU - Arós, Fernando AU - Ortega-Calvo, Manuel AU - Serra-Majem, Lluís AU - Gómez-Gracia, Enrique AU - Portolés, Olga AU - Fiol, Miquel AU - Díez Espino, Javier AU - Basora, Josep AU - Fitó, Montserrat AU - Ros, Emilio AU - Ordovás, José M PY - 2016 DO - 10.3390/nu8120793 UR - https://hdl.handle.net/10668/25674 T2 - Nutrients AB - Nutrigenetic studies analyzing gene-diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by obesity. Moreover,... LA - en KW - PREDIMED study KW - T2D-genetic risk scores KW - TCF7L2 KW - TCF7L2-predictive value KW - obesity KW - type-2 diabetes KW - Adult KW - Aged KW - Aged, 80 and over KW - Diabetes Mellitus, Type 2 KW - Female KW - Genetic Heterogeneity KW - Genetic Markers KW - Genetic Predisposition to Disease KW - Genetic Variation KW - Humans KW - Incidence KW - Longitudinal Studies KW - Male KW - Middle Aged KW - Nutrigenomics KW - Obesity KW - Polymorphism, Genetic KW - Predictive Value of Tests KW - Prevalence KW - Prospective Studies KW - Risk Factors KW - Transcription Factor 7-Like 2 Protein TI - Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores. TY - research article VL - 8 ER -