TY - JOUR AU - Rodríguez-Galán, Olga AU - García-Gómez, Juan J. AU - Rosado, Iván V. AU - Wei, Wu AU - Méndez-Godoy, Alfonso AU - Pillet, Benjamin AU - Alekseenko, Alisa AU - Steinmetz, Lars M. AU - Pelechano, Vicent AU - Kressler, Dieter AU - de la Cruz, Jesús PY - 2020 DO - 10.1093/nar/gkaa1200 SN - 0305-1048 UR - http://hdl.handle.net/10668/4574 T2 - Nucleic Acids Research AB - Proteostasis needs to be tightly controlled to meet the cellular demand for correctly de novo folded proteins and to avoid protein aggregation. While a coupling between translation rate and co-translational folding, likely involving an interplay... LA - en PB - Oxford University Presss on behalf of Nucleic Acids Research. KW - Alleles KW - Ribosomes KW - Proteostasis KW - Mutation KW - Saccharomyces cerevisiae KW - Protein folding KW - Molecular chaperones KW - Alelos KW - Ribosomas KW - Mutación KW - Proteínas de saccharomyces cerevisiae KW - Pliegue de proteína KW - Chaperonas moleculares KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Molecular Chaperones KW - Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Multiprotein Complexes KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation::Mutation, Missense KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Peptide Biosynthesis::Protein Biosynthesis::Peptide Chain Elongation, Translational KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation::Point Mutation KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Recombinant Proteins KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Ribosomal Proteins KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Ribosomes KW - Medical Subject Headings::Organisms::Eukaryota::Fungi::Ascomycota::Saccharomycetales::Saccharomyces::Saccharomyces cerevisiae KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Fungal Proteins::Saccharomyces cerevisiae Proteins KW - Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Biophysical Phenomena::Biophysical Processes::Protein Folding KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Acyltransferases::Aminoacyltransferases::Peptidyl Transferases KW - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Proteostasis Deficiencies KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::Solvents KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides TI - A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae TY - research article ER -