TY - GEN AU - Leon, Silvia AU - Tena-Sempere, Manuel PY - 2015 DO - 10.3389/fendo.2015.00189 SN - 1664-2392 UR - http://hdl.handle.net/10668/19216 T2 - Frontiers in endocrinology AB - Reproduction is essential for perpetuation of the species and, hence, is controlled by a sophisticated network of regulatory factors of central and peripheral origin that integrate at the hypothalamic-pituitary-gonadal (HPG) axis. Among the central... LA - en PB - Frontiers Research Foundation KW - GnIH KW - RFRP KW - NPFF receptors KW - RF9 KW - Kisspeptin KW - GnRH KW - Gonadotropins KW - Rfamide-related peptide-3 KW - Neuropeptide ff KW - Hypophysiotropic role KW - Physiological roles KW - Kisspeptin neurons KW - Cognate receptor KW - Gene-expression KW - Cdna cloning KW - Lh-secretion KW - Female rats TI - Dissecting the Roles of Gonadotropin-Inhibitory Hormone in Mammals: Studies Using Pharmacological Tools and Genetically Modified Mouse Models TY - review VL - 6 ER -