TY - JOUR AU - Bachiller, S AU - Hidalgo, I AU - Garcia, M G AU - Boza-Serrano, A AU - Paulus, A AU - Denis, Q AU - Haikal, C AU - Manouchehrian, O AU - Klementieva, O AU - Li, J Y AU - Pronk, C J AU - Gouras, G K AU - Deierborg, T PY - 2022 DO - 10.1186/s12974-022-02515-w UR - http://hdl.handle.net/10668/20332 T2 - Journal of neuroinflammation AB - The risk of developing Alzheimer's disease (AD) is modulated by genetic and environmental factors. Early-life stress (ELS) exposure during critical periods of brain development can impact later brain function and health, including increasing the risk... LA - en KW - Alzheimer’s disease KW - Early-life stress KW - Immunity KW - Maternal separation KW - Neuroinflammation KW - Sex differences KW - Animals KW - Female KW - Male KW - Mice KW - Alzheimer Disease KW - Amyloid beta-Peptides KW - Brain KW - Disease Models, Animal KW - Maternal Deprivation KW - Mice, Transgenic KW - Stress, Psychological KW - Sex Factors TI - Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner. TY - research article VL - 19 ER -