RT Journal Article T1 Health-related quality of life and utility outcomes with selinexor in relapsed/refractory diffuse large B-cell lymphoma. A1 Shah, Jatin A1 Shacham, Sharon A1 Kauffman, Michael A1 Daniele, Patrick A1 Tomaras, Dimitrios A1 Tremblay, Gabriel A1 Casasnovas, Rene-Olivier A1 Maerevoet, Marie A1 Zijlstra, Josee A1 Follows, George A1 P Vermaat, Joost S A1 Kalakonda, Nagesh A1 Goy, Andre Henri A1 Choquet, Sylvain A1 Den Neste, Eric Van A1 Hill, Brian T A1 Thieblemont, Catherine A1 Cavallo, Federica A1 la Cruz, Fátima de A1 Kuruvilla, John A1 Hamad, Nada A1 Bouabdallah, Reda A1 Jäger, Ulrich A1 Caimi, Paolo A1 Gurion, Ronit A1 Warzocha, Krzysztof A1 Bakhshi, Sameer A1 Sancho, Juan Manuel A1 Schuster, Michael A1 Egyed, Miklós A1 Offner, Fritz A1 Vasilakopoulos, Theodoros P A1 Samal, Priyanka A1 Nagy, Agnes A1 Ku, Matthew A1 Canales Albendea, Miguel Ángel K1 EQ-5D-5L K1 FACT-Lym K1 diffuse large B-cell lymphoma K1 disutility of adverse events K1 health state utility K1 health utility K1 health-related quality of life K1 patient-reported outcomes K1 selinexor AB Aim: Evaluate health-related quality of life (HRQoL) and health utility impact of single-agent selinexor in heavily pretreated patients with relapsed/refractory diffuse large B-cell lymphoma. Patients & methods: Functional Assessment of Cancer Therapy (FACT) - Lymphoma and EuroQoL five-dimensions five-levels data collected in the single-arm Phase IIb trial SADAL (NCT02227251) were analyzed with mixed-effects models. Results: Treatment responders maintained higher FACT - Lymphoma (p ≤ 0.05), FACT - General (p  YR 2021 FD 2021-02-02 LK http://hdl.handle.net/10668/17083 UL http://hdl.handle.net/10668/17083 LA en DS RISalud RD Apr 19, 2025