%0 Journal Article %A Shah, Jatin %A Shacham, Sharon %A Kauffman, Michael %A Daniele, Patrick %A Tomaras, Dimitrios %A Tremblay, Gabriel %A Casasnovas, Rene-Olivier %A Maerevoet, Marie %A Zijlstra, Josee %A Follows, George %A P Vermaat, Joost S %A Kalakonda, Nagesh %A Goy, Andre Henri %A Choquet, Sylvain %A Den Neste, Eric Van %A Hill, Brian T %A Thieblemont, Catherine %A Cavallo, Federica %A la Cruz, Fátima de %A Kuruvilla, John %A Hamad, Nada %A Bouabdallah, Reda %A Jäger, Ulrich %A Caimi, Paolo %A Gurion, Ronit %A Warzocha, Krzysztof %A Bakhshi, Sameer %A Sancho, Juan Manuel %A Schuster, Michael %A Egyed, Miklós %A Offner, Fritz %A Vasilakopoulos, Theodoros P %A Samal, Priyanka %A Nagy, Agnes %A Ku, Matthew %A Canales Albendea, Miguel Ángel %T Health-related quality of life and utility outcomes with selinexor in relapsed/refractory diffuse large B-cell lymphoma. %D 2021 %U http://hdl.handle.net/10668/17083 %X Aim: Evaluate health-related quality of life (HRQoL) and health utility impact of single-agent selinexor in heavily pretreated patients with relapsed/refractory diffuse large B-cell lymphoma. Patients & methods: Functional Assessment of Cancer Therapy (FACT) - Lymphoma and EuroQoL five-dimensions five-levels data collected in the single-arm Phase IIb trial SADAL (NCT02227251) were analyzed with mixed-effects models. Results: Treatment responders maintained higher FACT - Lymphoma (p ≤ 0.05), FACT - General (p  %K EQ-5D-5L %K FACT-Lym %K diffuse large B-cell lymphoma %K disutility of adverse events %K health state utility %K health utility %K health-related quality of life %K patient-reported outcomes %K selinexor %~