RT Journal Article
T1 25-hydroxyvitamin D levels in the early healing of osteoporotic hip fracture and their relationship with clinical outcome.
T2 Niveles de 25-hidroxivitamina D en la fase precoz de la fractura osteoporótica de cadera y su relación con los resultados clínicos.
A1 Carrillo González, Irene
A1 Martínez-Ramírez, María José
A1 Tenorio Jiménez, Carmen
A1 Delgado Martínez, Alberto Damián
A1 Aguilar Peña, Rosario
A1 Madrigal Cueto, Rosa
A1 Delgado-Rodríguez, Miguel
K1 Vitamina D3. Fracturas osteoporóticas. Nivel cognitivo. Estancia hospitalaria.
AB Introduction: vitamin D is involved in recovery after an osteoporotic hip fracture (OHF). Previous studies have reported decreased serum vitamin D levels during fracture healing. Objectives: our aim was to evaluate: a) serum 25-hydroxyvitamin D3 (25OHD3) levels in patients with OHF at hospital admission and 8 days post-admission, and b) the relationship between 25OHD levels and clinical outcomes. Methods: a prospective study including 66 patients aged over 65 years hospitalized for OHF. We gathered data on baseline demographic characteristics, medical history, Mini Mental State (MMS) assessment, Activities of Daily Living (ADL) results, nutritional assessment, and type of fracture and surgery. Laboratory results were collected on bone biomarkers, albumin, 25OHD3, and IL6. Clinical outcomes included length of stay, complications, and mortality. In the statistical analysis, a t-test was used for continuous variables and a chi-square test for qualitative variables. Linear regression models were used for the multivariate analysis, adjusted for covariates. Results: our study population had low serum vitamin D levels at admission, with a mean [(standard error of the mean (SEM)] of 12.04 (1.03) ng/mL. Both 25OHD3 and interleukin 6 (IL-6) levels significantly declined (p
YR 2020
FD 2020
LK http://hdl.handle.net/10668/14973
UL http://hdl.handle.net/10668/14973
LA en
DS RISalud
RD Apr 5, 2025