TY  - JOUR
AU  - Ibañez-Costa, Alejandro
AU  - Lopez-Sanchez, Laura M
AU  - Gahete, Manuel D
AU  - Rivero-Cortes, Esther
AU  - Vazquez-Borrego, Mari C
AU  - Galvez, Maria A
AU  - de-la-Riva, Andres
AU  - Venegas-Moreno, Eva
AU  - Jimenez-Reina, Luis
AU  - Moreno-Carazo, Alberto
AU  - Tinahones, Francisco J
AU  - Maraver-Selfa, Silvia
AU  - Japon, Miguel A
AU  - Garcia-Arnes, Juan A
AU  - Soto-Moreno, Alfonso
AU  - Webb, Susan M
AU  - Kineman, Rhonda D
AU  - Culler, Michael D
AU  - Castaño, Justo P
AU  - Luque, Raul M
PY  - 2017
DO  - 10.1038/srep42002
UR  - http://hdl.handle.net/10668/2675
T2  - Scientific Reports
AB  - Chimeric somatostatin/dopamine compounds such as BIM-23A760, an sst2/sst5/D2 receptors-agonist, have emerged as promising new approaches to treat pituitary adenomas. However, information on direct in vitro effects of BIM-23A760 in normal and tumoral...
LA  - en
PB  - Nature Publishing Group
KW  -  Pituitary Neoplasms
KW  -  Dopamine
KW  -  Receptors, Somatostatin
KW  -  Cell Survival 
KW  - Somatostatin
KW  -  Adenoma
KW  - Medical Subject Headings::Diseases::Endocrine System Diseases::Endocrine Gland Neoplasms::Pituitary Neoplasms::ACTH-Secreting Pituitary Adenoma
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amines::Catecholamines::Dopamine
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pituitary Hormones
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates
TI  - BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas
TY  - research article
ER  -