RT Journal Article T1 Neighbourhood walkability and physical activity: moderating role of a physical activity intervention in overweight and obese older adults with metabolic syndrome. A1 Colom, Antoni A1 Mavoa, Suzanne A1 Ruiz, Maurici A1 Wärnberg, Julia A1 Muncunill, Josep A1 Konieczna, Jadwiga A1 Vich, Guillem A1 Barón-López, Francisco Javier A1 Fitó, Montserrat A1 Salas-Salvadó, Jordi A1 Romaguera, Dora K1 PREDIMED-Plus trial K1 built environment K1 longitudinal study K1 older people K1 physical activity intervention K1 walkability index AB While urban built environments might promote active ageing, an infrequently studied question is how the neighbourhood walkability modulates physical activity changes during a physical activity intervention programme in older adults. We assessed the influence of objectively assessed neighbourhood walkability on the change in physical activity during the intervention programme used in the ongoing PREvención con DIeta MEDiterránea (PREDIMED)-Plus trial. The present study involved 228 PREDIMED-Plus senior participants aged between 55 and 75, recruited in Palma de Mallorca (Spain). Overweight/obese older adults with metabolic syndrome were randomised to an intensive weight-loss lifestyle intervention or a control group. A walkability index (residential density, land use mix, intersections density) was calculated using geographic information systems (1 km sausage-network buffer). Physical activity was assessed using accelerometer and a validated questionnaire, at baseline and two follow-up visits (6-months and 1-year later). Generalised additive mixed models were fitted to estimate the association between the neighbourhood walkability index and changes in physical activity during follow-up. Higher neighbourhood walkability (1 z-score increment) was associated with moderate-to-vigorous accelerometer assessed physical activity duration, (β = 3.44; 95% CI = 0.52; 6.36 min/day). When analyses were stratified by intervention arm, the association was only observed in the intervention group (β = 6.357; 95% CI = 2.07;10.64 min/day) (P for interaction = 0.055). The results indicate that the walkability of the neighbourhood could support a physical activity intervention, helping to maintain or increase older adults' physical activity. YR 2021 FD 2021 LK http://hdl.handle.net/10668/16637 UL http://hdl.handle.net/10668/16637 LA en DS RISalud RD Apr 15, 2025