TY  - JOUR
AU  - Lorenzo, Petra I.
AU  - Martin Vazquez, Eugenia
AU  - López-Noriega, Livia
AU  - Fuente-Martín, Esther
AU  - Mellado-Gil, José M.
AU  - Franco, Jaime M.
AU  - Cobo-Vuilleumier, Nadia
AU  - Guerrero Martínez, José A.
AU  - Romero-Zerbo, Silvana Y.
AU  - Perez-Cabello, Jesús A.
AU  - Rivero Canalejo, Sabrina
AU  - Campos-Caro, Antonio
AU  - Lachaud, Christian Claude
AU  - Crespo Barreda, Alejandra
AU  - Aguilar-Diosdado, Manuel
AU  - García Fuentes, Eduardo
AU  - Martin-Montalvo, Alejandro
AU  - Álvarez Dolado, Manuel
AU  - Martin, Franz
AU  - Rojo-Martinez, Gemma
AU  - Pozo, David
AU  - Bérmudez-Silva, Francisco J.
AU  - Comaills, Valentine
AU  - Reyes, José C.
AU  - Gauthier, Benoit R.
PY  - 2021
DO  - 10.7150/thno.57237
UR  - http://hdl.handle.net/10668/3492
T2  - Theranostics
AB  - Rationale: We recently demonstrated that the 'Metabesity' factor HMG20A regulates islet beta-cell functional maturity and adaptation to physiological stress such as pregnancy and pre-diabetes. HMG20A also dictates central nervous system (CNS)...
LA  - en
PB  - Ivyspring International Publisher
KW  - HMG20A
KW  - ORY1001
KW  - Metabolism
KW  - Metabesity
KW  - Astrocytes
KW  - Inflammation
KW  - Metabolismo
KW  - Astrocitos
KW  - Inflamación
KW  - Adipose Tissue
KW  - Medical Subject Headings::Persons::Persons::Age Groups::Adult
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Anatomy::Nervous System::Neuroglia::Astrocytes
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::Repressor Proteins::Co-Repressor Proteins
KW  - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet::Diet, High-Fat
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Gliosis
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nuclear Proteins::Chromosomal Proteins, Non-Histone::High Mobility Group Proteins
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on CH-NH Group Donors::Oxidoreductases, N-Demethylating::Histone Demethylases
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hypothalamus
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-1::Interleukin-1beta
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Inbred Strains
KW  - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Middle Aged
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nerve Tissue Proteins
KW  - Medical Subject Headings::Anatomy::Nervous System::Neurons
KW  - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity
KW  - RNA-Seq
KW  - Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Glycosides::Glucosides
TI  - The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity
TY  - research article
ER  -