TY - JOUR AU - Sarmento-Cabral, Andre AU - L-Lopez, Fernando AU - Gahete, Manuel D AU - CastaƱo, Justo P AU - Luque, Raul M PY - 2017 DO - 10.1158/1541-7786.MCR-16-0493 UR - http://hdl.handle.net/10668/11061 T2 - Molecular cancer research : MCR AB - Prostate-cancer is strongly influenced by obesity, wherein metformin could represent a promising treatment; however, the endocrine metabolic/cellular/molecular mechanisms underlying these associations and effects are still unclear. To determine the... LA - en PB - American Association for Cancer Research KW - Animals KW - Apoptosis KW - Cell line, tumor KW - Diet, fat-restricted KW - Diet, high-fat KW - Humans KW - Insulin-like growth factor I KW - Male KW - Metformin KW - Mice KW - Obesity KW - Prostate KW - Prostatic neoplasms KW - Signal transduction KW - Xenograft model antitumor assays TI - Metformin Reduces Prostate Tumor Growth, in a Diet-Dependent Manner, by Modulating Multiple Signaling Pathways. TY - research article VL - 15 ER -