TY - JOUR AU - Cáliz, Rafael AU - Canet, Luz María AU - Lupiañez, Carmen Belén AU - Canhão, Helena AU - Escudero, Alejandro AU - Filipescu, Ileana AU - Segura-Catena, Juana AU - Soto-Pino, María José AU - Expósito-Ruiz, Manuela AU - Ferrer, Miguel Ángel AU - García, Antonio AU - Romani, Lurdes AU - González-Utrilla, Alfonso AU - Vallejo, Teresa AU - Pérez-Pampin, Eva AU - Hemminki, Kari AU - Försti, Asta AU - Collantes, Eduardo AU - Fonseca, João Eurico AU - Sainz, Juan PY - 2013 DO - 10.1371/journal.pone.0072732 UR - http://hdl.handle.net/10668/1345 T2 - PloS one AB - The present study was conducted to explore whether single nucleotide polymorphisms (SNPs) in Th1 and Th17 cell-mediated immune response genes differentially influence the risk of rheumatoid arthritis (RA) in women and men. In phase one, 27... LA - en PB - Public Library of Science KW - Artritis Reumatoide KW - Polimorfismo de Nucleótido Simple KW - Células Th17 KW - Células TH1 KW - Genotipo KW - Lectinas KW - Riesgo KW - Femenino KW - Masculino KW - Predisposición Genética a la Enfermedad KW - Humanos KW - Medical Subject Headings::Diseases::Immune System Diseases::Autoimmune Diseases::Arthritis, Rheumatoid KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide KW - Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::T-Lymphocyte Subsets::T-Lymphocytes, Helper-Inducer::Th17 Cells KW - Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::T-Lymphocyte Subsets::T-Lymphocytes, Helper-Inducer::Th1 Cells KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Lectins KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans TI - Gender-Specific Effects of Genetic Variants within Th1 and Th17 Cell-Mediated Immune Response Genes on the Risk of Developing Rheumatoid Arthritis. TY - research article ER -