TY - JOUR AU - Tessier, Sarah AU - Ferhi, Omar AU - Geoffroy, Marie-Claude AU - González-Prieto, Román AU - Canat, Antoine AU - Quentin, Samuel AU - Pla, Marika AU - Niwa-Kawakita, Michiko AU - Bercier, Pierre AU - Rérolle, Domitille AU - Tirard, Marilyn AU - Therizols, Pierre AU - Fabre, Emmanuelle AU - Vertegaal, Alfred C O AU - de Thé, Hugues AU - Lallemand-Breitenbach, Valérie PY - 2022 DO - 10.1038/s41467-022-33147-6 UR - http://hdl.handle.net/10668/19546 T2 - Nature communications AB - Membrane-less organelles are condensates formed by phase separation whose functions often remain enigmatic. Upon oxidative stress, PML scaffolds Nuclear Bodies (NBs) to regulate senescence or metabolic adaptation. PML NBs recruit many partner... LA - en KW - Animals KW - Arsenic KW - DNA Transposable Elements KW - Embryonic Stem Cells KW - Mice KW - Nuclear Bodies KW - Sumoylation KW - Transcription Factors TI - Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells. TY - research article VL - 13 ER -