TY  - JOUR
AU  - Borrego, Lorenzo G
AU  - Recio, Rocío
AU  - Moreno, Nazaret
AU  - Chelouan, Ahmed
AU  - Álvarez, Eleuterio
AU  - Sánchez-Coronilla, Antonio
AU  - Caro, Carlos
AU  - Pearson, John R
AU  - García-Martín, Maria Luisa
AU  - Khiar, Noureddine
AU  - Fernández, Inmaculada
PY  - 2022
DO  - 10.1016/j.ejmech.2022.114730
UR  - http://hdl.handle.net/10668/22187
T2  - European journal of medicinal chemistry
AB  - The stereoselective addition of ethyl acetate enolate to the C═N bond of N-tert-butylsulfinylimines has been investigated in depth. A significant effect of the LHMDS amount and the N-sulfinylimine nature on the stereoselectivity of the process was...
LA  - en
KW  - Enantiopure 4-amino-3,4-dihydrocoumarins
KW  - Glioblastoma multiforme
KW  - N-sulfinylarylimines
KW  - β-hydroxyesters
KW  - Humans
KW  - Glioblastoma
KW  - Stereoisomerism
KW  - Esters
KW  - Antineoplastic Agents
TI  - Enantioselective synthesis of 4-amino-3,4-dihydrocoumarins and their non-cyclic hydroxyester precursors: Biological evaluation for the treatment of glioblastoma multiforme.
TY  - research article
VL  - 243
ER  -