TY  - JOUR
AU  - Varela-Eirin, Marta
AU  - Carpintero-Fernandez, Paula
AU  - Sanchez-Temprano, Agustin
AU  - Varela-Vazquez, Adrian
AU  - Paino, Carlos Luis
AU  - Casado-Diaz, Antonio
AU  - Calañas-Continente, Alfonso
AU  - Mato, Virginia
AU  - Fonseca, Eduardo
AU  - Kandouz, Mustapha
AU  - Blanco, Alfonso
AU  - Caeiro, Jose Ramon
AU  - Mayan, Maria D
PY  - 2020
DO  - 10.18632/aging.103801
UR  - http://hdl.handle.net/10668/16037
T2  - Aging
AB  - Articular cartilage and synovial tissue from patients with osteoarthritis (OA) show an overactivity of connexin43 (Cx43) and accumulation of senescent cells associated with disrupted tissue regeneration and disease progression. The aim of this study...
LA  - en
PB  - Impact Journals LLC
KW  - Connexin43
KW  - Dedifferentiation
KW  - Osteoarthritis
KW  - Senescence
KW  - Tissue regeneration
KW  - Aged
KW  - Antirheumatic agents
KW  - Cartilage, articular
KW  - Cell differentiation
KW  - Cell line
KW  - Cellular microenvironment
KW  - Cellular senescence
KW  - Chondrocytes
KW  - Chondrogenesis
KW  - Collagen Type II
KW  - Connexin 43
KW  - Female
KW  - Fruit
KW  - Humans
KW  - Iridoid glucosides
KW  - Iridoids
KW  - Male
KW  - NF-kappa B
KW  - Nuclear proteins
KW  - Olea
KW  - Osteoarthritis
KW  - Osteogenesis
KW  - Polyphenols
KW  - Regeneration
KW  - Signal transduction
KW  - Twist-related protein 1
TI  - Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis.
TY  - research article
VL  - 12
ER  -