TY - JOUR AU - Lindström, Sara AU - Ma, Jing AU - Altshuler, David AU - Giovannucci, Edward AU - Riboli, Elio AU - Albanes, Demetrius AU - Allen, Naomi E AU - Berndt, Sonja I AU - Boeing, Heiner AU - Bueno de Mesquita, H Bas AU - Chanock, Stephen J AU - Dunning, Alison M AU - Spencer Feigelson, Heather AU - Gaziano, J Michael AU - Haiman, Christopher A AU - Hayes, Richard B AU - Henderson, Brian E AU - Hunter, David J AU - Kaaks, Rudolf AU - Kolonel, Laurence N AU - Le Marchand, Loic AU - Martínez, Carmen AU - Overvad, Kim AU - Siddiq, Afshan AU - Stampfer, Meir AU - Stattin, Pär AU - Stram, Daniel O AU - Thun, Michael J AU - Trichopoulos, Dimitrios AU - Tumino, Rosario AU - Virtamo, Jarmo AU - Weinstein, Stephanie J AU - Yeager, Meredith AU - Kraft, Peter AU - Freedman, Matthew L PY - 2010 DO - 10.1210/jc.2009-1911 UR - http://hdl.handle.net/10668/392 T2 - Journal of Clinical Endocrinology and Metabolism AB - Background: Androgens are key regulators of prostate gland maintenance and prostate cancer growth, and androgen deprivation therapy has been the mainstay of treatment for advanced prostate cancer for many years. A long-standing hypothesis has been... LA - es PB - Endocrine Society KW - Neoplasias de la próstata KW - Hormonas esteroides gonadales KW - Receptores androgénicos KW - Estudios de asociación genética KW - Estudios de cohortes KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Genital Neoplasms, Male::Prostatic Neoplasms KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Receptors, Cytoplasmic and Nuclear::Receptors, Steroid::Receptors, Androgen KW - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Gonadal Hormones::Gonadal Steroid Hormones KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Genetic Association Studies KW - Medical Subject Headings::Health Care::Health Care Economics and Organizations::Organizations::Government::Federal Government::United States Government Agencies::United States Dept. of Health and Human Services::National Institutes of Health... KW - Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies TI - A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium TY - research article ER -