TY - JOUR AU - Arroyo, Noelia AU - Villamayor, Laura AU - Díaz, Irene AU - Carmona, Rita AU - Ramos-Rodríguez, Mireia AU - Muñoz-Chápuli, Ramón AU - Pasquali, Lorenzo AU - Toscano, Miguel G. AU - Martín, Franz AU - Cano, David A. AU - Rojas, Anabel PY - 2021 DO - 10.1172/jci.insight.150059 UR - http://hdl.handle.net/10668/4581 T2 - JCI Insight AB - In response to liver injury, hepatic stellate cells activate and acquire proliferative and contractile features. The regression of liver fibrosis appears to involve the clearance of activated hepatic stellate cells, either by apoptosis or by reversion... LA - en PB - American Society for Clinical Investigation KW - Liver cirrhosis KW - Hepatocytes KW - Hepatic stellate cells KW - GATA4 transcription factor KW - Mice KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::GATA Transcription Factors::GATA4 Transcription Factor KW - Medical Subject Headings::Anatomy::Cells::Hepatic Stellate Cells KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Diseases::Digestive System Diseases::Liver Diseases::Liver Cirrhosis KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Recombination, Genetic::Transfection KW - Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Hepatocytes TI - GATA4 induces liver fibrosis regression by deactivating hepatic stellate cells TY - research article ER -