RT Journal Article
T1 Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity.
A1 Torres, María José
A1 Trautmann, Axel
A1 Böhm, Ingrid
A1 Scherer, Kathrin
A1 Barbaud, Annick
A1 Bavbek, Sevim
A1 Bonadonna, Patrizia
A1 Cernadas, Josefina Rodrigues
A1 Chiriac, Anca Mirela
A1 Gaeta, Francesco
A1 Gimenez-Arnau, Ana M
A1 Kang, Hye-Ryun
A1 Moreno, Esther
A1 Brockow, Knut
K1 IgE
K1 Iodinated contrast media
K1 T cells
K1 allergy
K1 diagnosis
K1 hypersensitivity
K1 management
AB Immediate and nonimmediate hypersensitivity reactions to iodinated contrast media (ICM) have been reported to occur in a frequency of about 0.5%-3% of patients receiving nonionic ICM. The diagnosis and management of these patients vary among guidelines published by various national and international scientific societies, with recommendations ranging from avoidance or premedication to drug provocation test. This position paper aims to give recommendations for the management of patients with ICM hypersensitivity reactions and analyze controversies in this area. Skin tests are recommended as the initial step for diagnosing patients with immediate and nonimmediate hypersensitivity reactions; besides, they may also help guide on tolerability of alternatives. Re-exposition or drug provocation test should only be done with skin test-negative ICMs. The decision for performing either re-exposition or drug provocation test needs to be taken based on a risk-benefit analysis. The role of in vitro tests for diagnosis and pretreatment for preventing reactions remains controversial.
YR 2021
FD 2021
LK http://hdl.handle.net/10668/16581
UL http://hdl.handle.net/10668/16581
LA en
DS RISalud
RD Apr 11, 2025