TY - JOUR AU - Nabi, Dalileh AU - Drechsler, Hauke AU - Pschirer, Johannes AU - Korn, Franz AU - Schuler, Nadine AU - Diez, Stefan AU - Jessberger, Rolf AU - Chacón, Mariola PY - 2021 DO - 10.1038/s41467-021-26826-3 UR - http://hdl.handle.net/10668/4413 T2 - Nature Communications AB - Proper chromosome segregation is essential to avoid aneuploidy, yet this process fails with increasing age in mammalian oocytes. Here we report a role for the scarcely described protein CENP-V in oocyte spindle formation and chromosome segregation. We... LA - en PB - Springer Nature KW - Chromosome segregation KW - Microtubules KW - Oocytes KW - Aneuploidy KW - Metaphase KW - Spindle poles KW - Segregación cromosómica KW - Microtúbulos KW - Oocitos KW - Aneuploidia KW - Metafase KW - Polos del huso mitótico KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Cell Division::Cell Nucleus Division::Chromosome Segregation KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Cycle Checkpoints::M Phase Cell Cycle Checkpoints KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Division::Cell Nucleus Division::Meiosis KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Division::Cell Nucleus Division::Metaphase KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Cytoskeleton::Microtubule-Organizing Center KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Cytoskeleton::Microtubules KW - Medical Subject Headings::Anatomy::Cells::Germ Cells::Ovum::Oocytes TI - CENP-V is required for proper chromosome segregation through interaction with spindle microtubules in mouse oocytes TY - research article ER -