RT Journal Article T1 A combined analysis of the short-term effects of photochemical air pollutants on mortality within the EMECAM project. A1 Saez, Marc A1 Ballester, Ferran A1 Barceló, Maria Antònia A1 Pérez-Hoyos, Santiago A1 Bellido, Juan A1 Tenías, José María A1 Ocaña, Ricardo A1 Figueiras, Adolfo A1 Arribas, Federico A1 Aragonés, Nuria A1 Tobías, Aurelio A1 Cirera, Lluís A1 Cañada, Alvaro K1 Oxidantes Fotoquímicos K1 Ozono K1 Dióxido de Nitrógeno K1 Contaminantes del Aire K1 España AB In recent years, some epidemiologic studies have attributed adverse effects of air pollutants on health not only to particles and sulfur dioxide but also to photochemical air pollutants (nitrogen dioxide and ozone). The effects are usually small, leading to some inconsistencies in the results of the studies. Furthermore, the different methodologic approaches of the studies used has made it difficult to derive generic conclusions. We provide here a quantitative summary of the short-term effects of photochemical air pollutants on mortality in seven Spanish cities involved in the EMECAM project, using generalized additive models from analyses of single and multiple pollutants. Nitrogen dioxide and ozone data were provided by seven EMECAM cities (Barcelona, Gijón, Huelva, Madrid, Oviedo, Seville, and Valencia). Mortality indicators included daily total mortality from all causes excluding external causes, daily cardiovascular mortality, and daily respiratory mortality. Individual estimates, obtained from city-specific generalized additive Poisson autoregressive models, were combined by means of fixed effects models and, if significant heterogeneity among local estimates was found, also by random effects models. Significant positive associations were found between daily mortality (all causes and cardiovascular) and NO(2), once the rest of air pollutants were taken into account. A 10 microg/m(3) increase in the 24-hr average 1-day NO(2)level was associated with an increase in the daily number of deaths of 0.43% [95% confidence interval (CI), -0.003-0.86%] for all causes excluding external. In the case of significant relationships, relative risks for cause-specific mortality were nearly twice as much as that for total mortality for all the photochemical pollutants. Ozone was independently related only to cardiovascular daily mortality. No independent statistically significant relationship between photochemical air pollutants and respiratory mortality was found. The results in this study suggest that, given the present levels of photochemical pollutants, people living in Spanish cities are exposed to health risks derived from air pollution. PB National Institute of Environmental Health Sciences (NIEHS) SN 0091-6765 YR 2002 FD 2002-03 LK http://hdl.handle.net/10668/1907 UL http://hdl.handle.net/10668/1907 LA en NO Saez M, Ballester F, Barceló MA, Pérez-Hoyos S, Bellido J, Tenías JM, et al. A combined analysis of the short-term effects of photochemical air pollutants on mortality within the EMECAM project. Environ Health Perspect. 2002; 110(3):221-8 NO Journal Article; Research Support, Non-U.S. Gov't; DS RISalud RD Apr 7, 2025