RT Journal Article
T1 Obstetric outcomes in pregnant women diagnosed of antiphospholipid syndrome
A1 Felix, Cristina
A1 Paz Carrillo, Maria
A1 Anon, Isabel
A1 Javier Malde, Francisco
A1 Caliz, Rafael
A1 Puertas, Alberto
K1 Antiphospholipidid Syndrome
K1 Antiphospholipid Antibodies
K1 Pregnancy
K1 High Risk Pregnancy
K1 Pregnancy Complications
K1 Risk-factors
K1 Heparin
K1 Metaanalysis
K1 Antibodies
K1 Anticardiolipin
K1 Multicenter
K1 Aspirin
AB Introduction; The antiphospholipid syndrome (APS) is an autoinmune disease characterized by the occurence of thrombosis, obstetric morbidity and the presence of antiphospholipid antibodies. The aim of this study was to evaluate the obstetric outcomes in pregnant women diagnosed of antiphospholipid syndrome, as well as examine the conditions which may influence in those results.Materials and methods: A retrospective study was undertaken with pregnant women diagnosed of APS, who were attended in our hospital between 2007 and 2017.Results: During the period of study 35 patients with APS and a sum of 50 pregnancies were gathered. Heparin was used in ail pregnancies and acetylsalicylic acid in 96%. Any adverse obstetric outcome occurred in 34% of the pregnancies in the study. The triple positivity of antiphospholipid antibodies was associated to higher percentage of premature deliveries. The lupus anticoagulant alone was not related to worse obstetric outcomes.Conclusions: Pregnancy in APS patients means a challenge, requiring a multidisciplinary management by Obstetnaans and Rheumathologists. On the other hand, the antiphospholipid antibodies profile could help to recognize those patient at risk, in order to adequate treatment and improve obstetric results.
PB Elsevier
YR 2021
FD 2021-02-01
LK https://hdl.handle.net/10668/26273
UL https://hdl.handle.net/10668/26273
LA es
DS RISalud
RD Apr 4, 2025