TY  - JOUR
AU  - Islam, Rakibul
AU  - Islam, Mohammad Mirazul
AU  - Nilsson, Per H
AU  - Mohlin, Camilla
AU  - Hagen, Kjersti Thorvaldsen
AU  - Paschalis, Eleftherios I
AU  - Woods, Russell L
AU  - Bhowmick, Sabuj Chandra
AU  - Dohlman, Claes H
AU  - Espevik, Terje
AU  - Chodosh, James
AU  - Gonzalez-Andrades, Miguel
AU  - Mollnes, Tom Eirik
PY  - 2021
DO  - 10.1016/j.actbio.2021.03.047
UR  - http://hdl.handle.net/10668/17429
T2  - Acta biomaterialia
AB  - Inadequate supplies of donor corneas have evoked an escalating interest in corneal xenotransplantation. However, innate immune responses contribute significantly to the mechanism of xenograft rejection. We hypothesized that complement component C5 and...
LA  - en
PB  - Elsevier
KW  - Biomaterial
KW  - Complement system
KW  - Cornea
KW  - Cytokine
KW  - Decellularization
KW  - Regenerative medicine
KW  - Toll-like receptor
KW  - Xenotransplantation
KW  - Animals
KW  - Complement C5
KW  - Cornea
KW  - Corneal transplantation
KW  - Cytokines
KW  - Heterografts
KW  - Humans
KW  - Inflammation
KW  - Lipopolysaccharide receptors
KW  - Swine
KW  - Transplantation, heterologous
TI  - Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses.
TY  - research article
VL  - 127
ER  -