RT Journal Article T1 SEOM clinical guidelines for diagnosis and treatment of metastatic colorectal cancer (2018). A1 Gomez-España, M A A1 Gallego, J A1 Gonzalez-Flores, E A1 Maurel, J A1 Paez, D A1 Sastre, J A1 Aparicio, J A1 Benavides, M A1 Feliu, J A1 Vera, R K1 Ablative treatments K1 Chemotherapy K1 Colorectal cancer K1 Frail patients K1 Metastases K1 Surgery K1 Targeted agents AB Colorectal cancer (CRC) is the second cause of cancer death in Spain, the objective of this guide published by the Spanish Society of Medical Oncology is to develop a consensus for the diagnosis and management of metastatic disease. The optimal treatment strategy for patients with metastatic CRC should be discussed in a multidisciplinary expert team to select the most appropriate treatment, and integrate systemic treatment and other options such as surgery and ablative techniques depending on the characteristics of the tumour, the patient and the location of the disease and metastases. PB Springer YR 2018 FD 2018-11-28 LK http://hdl.handle.net/10668/13328 UL http://hdl.handle.net/10668/13328 LA en NO Gómez-España MA, Gallego J, González-Flores E, Maurel J, Páez D, Sastre J, et al. SEOM clinical guidelines for diagnosis and treatment of metastatic colorectal cancer (2018). Clin Transl Oncol. 2019 Jan;21(1):46-54 DS RISalud RD Apr 5, 2025