TY - JOUR AU - Esteban-Medina, Marina AU - Peña-Chilet, María AU - Loucera, Carlos AU - Dopazo, Joaquín PY - 2019 DO - 10.1186/s12859-019-2969-0 UR - http://hdl.handle.net/10668/14209 T2 - BMC bioinformatics AB - In spite of the abundance of genomic data, predictive models that describe phenotypes as a function of gene expression or mutations are difficult to obtain because they are affected by the curse of dimensionality, given the disbalance between samples... LA - en KW - Big data KW - Fanconi anemia KW - Genomics KW - Machine learning KW - Mathematical models KW - Signaling pathways KW - Databases, Factual KW - Fanconi Anemia KW - Genomics KW - Humans KW - Machine Learning KW - Phenotype KW - Proteins KW - Signal Transduction TI - Exploring the druggable space around the Fanconi anemia pathway using machine learning and mechanistic models. TY - research article VL - 20 ER -