RT Journal Article T1 Sarcoidosis onset simulating a unique hepatic metastasis. A1 Diéguez Castillo, Carmelo A1 Martín-Lagos Maldonado, Alicia A1 Ríos Pelegrina, Rosa María A1 Díaz Alcázar, María Del Mar A1 Roa Colomo, Amparo A1 Ruiz Escolano, Elena AB Sarcoidosis is a systemic granulomatous disease with an uncertain etiology, characterized by the production of non-necrotizing granulomas. The most frequent presentation is pulmonary and mediastinal, although it might affect any other organ. Hepatic alterations occur in 50 to 65% of the cases. Nevertheless, it is commonly subclinical or detected during a study of the alteration of liver enzymes. It is very unusual that disease onset occurs as an isolated hepatic tumor. A hepatic biopsy is usually required to confirm the diagnosis. A differential diagnosis must be established via any hepatic granulomatous disease, infectious or autoimmune disease as well as the exclusion of malignancy. We present a clinical case of a female diagnosed with an isolated hepatic sarcoidosis that simulated a unique hepatic metastatic lesion. The hepatic biopsy was diagnostic. SN 1130-0108 YR 2018 FD 2018 LK https://hdl.handle.net/10668/26071 UL https://hdl.handle.net/10668/26071 LA en DS RISalud RD Apr 17, 2025