%0 Journal Article %A Diéguez Castillo, Carmelo %A Martín-Lagos Maldonado, Alicia %A Ríos Pelegrina, Rosa María %A Díaz Alcázar, María Del Mar %A Roa Colomo, Amparo %A Ruiz Escolano, Elena %T Sarcoidosis onset simulating a unique hepatic metastasis. %D 2018 %@ 1130-0108 %U https://hdl.handle.net/10668/26071 %X Sarcoidosis is a systemic granulomatous disease with an uncertain etiology, characterized by the production of non-necrotizing granulomas. The most frequent presentation is pulmonary and mediastinal, although it might affect any other organ. Hepatic alterations occur in 50 to 65% of the cases. Nevertheless, it is commonly subclinical or detected during a study of the alteration of liver enzymes. It is very unusual that disease onset occurs as an isolated hepatic tumor. A hepatic biopsy is usually required to confirm the diagnosis. A differential diagnosis must be established via any hepatic granulomatous disease, infectious or autoimmune disease as well as the exclusion of malignancy. We present a clinical case of a female diagnosed with an isolated hepatic sarcoidosis that simulated a unique hepatic metastatic lesion. The hepatic biopsy was diagnostic. %~