TY - JOUR AU - Silva, Joana AU - Aivio, Suvi AU - Knobel, Philip A AU - Bailey, Laura J AU - Casali, Andreu AU - Vinaixa, Maria AU - Garcia-Cao, Isabel AU - Coyaud, Etienne AU - Jourdain, Alexis A AU - Perez-Ferreros, Pablo AU - Rojas, Ana M AU - Antolin-Fontes, Albert AU - Samino-Gene, Sara AU - Raught, Brian AU - Gonzalez-Reyes, Acaimo AU - Ribas-de-Pouplana, Lluis AU - Doherty, Aidan J AU - Yanes, Oscar AU - Stracker, Travis H PY - 2018 DO - 10.1038/s41556-017-0016-9 UR - http://hdl.handle.net/10668/12015 T2 - Nature cell biology AB - Mitochondria are subcellular organelles that are critical for meeting the bioenergetic and biosynthetic needs of the cell. Mitochondrial function relies on genes and RNA species encoded both in the nucleus and mitochondria, and on their coordinated... LA - en PB - Nature Publishing Group KW - RNA metabolism KW - Mitochondria KW - Embryonic germ cells KW - Drosophila KW - Animals KW - Cell Nucleus KW - Drosophila Proteins KW - Drosophila melanogaster KW - Exonucleases KW - Germ Cells KW - Homeostasis KW - Longevity KW - Mitochondria KW - Mitochondrial Proteins KW - Mitochondrial Ribosomes KW - Protein Biosynthesis KW - RNA, Messenger KW - Reactive Oxygen Species KW - Stem Cells TI - EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. TY - research article VL - 20 ER -