TY - JOUR AU - Ghorashian, Sara AU - Jacoby, Elad AU - De-Moerloose, Barbara AU - Rives, Susana AU - Bonney, Denise AU - Shenton, Geoff AU - Bader, Peter AU - Bodmer, Nicole AU - Molinos-Quintana, Agueda AU - Herrero, Blanca AU - Algeri, Mattia AU - Locatelli, Franco AU - Vettenranta, Kim AU - Gonzalez, Berta AU - Attarbaschi, Andishe AU - Harris, Stephen AU - Bourquin, Jean Pierre AU - Baruchel, Andre PY - 2022 DO - 10.1016/S2352-3026(22)00225-3 UR - http://hdl.handle.net/10668/22560 T2 - The Lancet. Haematology AB - Children aged younger than 3 years were excluded from the ELIANA phase 2 trial of tisagenlecleucel in children with acute lymphoblastic leukaemia. The feasibility, safety, and activity of tisagenlecleucel have not been defined in this group, the... LA - en PB - The Lancet Publishing Group KW - Tisagenlecleucel KW - Infant Acute Lymphoblastic Leukemia KW - KMT2A-Rearranged Leukemia KW - CAR T-Cell Therapy KW - Overall Survival KW - Event-Free Survival KW - B-Cell Aplasia KW - Cytokine Release Syndrome KW - Neurotoxicity KW - Child, Preschool KW - Humans KW - Infant KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma KW - Receptors, Antigen, T-Cell KW - Receptors, Chimeric Antigen KW - Retrospective Studies TI - Tisagenlecleucel therapy for relapsed or refractory B-cell acute lymphoblastic leukaemia in infants and children younger than 3 years of age at screening: an international, multicentre, retrospective cohort study. TY - research article VL - 9 ER -